Organooxygen compounds
eMolecules N-Acetyl-S-(2-hydroxyethyl)-L-cysteine Dicyclohexylammonium Salt | 1331896-18-4 | MFCD28899225 | 250mg
Toronto Research Chemicals | N-Acetyl-S-(2-hydroxyethyl)-L-cysteine Dicyclohexylammonium Salt | 250mg | 486592001 | A178911 | | 1331896-18-4 | MFCD28899225 | 388.570 | C19H36N2O4S
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eMolecules Building Block Tool
Apexbio Technology LLC N-trans-Feruloyltyramine 66648-43-9 5mg
N-trans-Feruloyltyramine (CAS 66648-43-9) is a naturally occurring alkaloid recognized for its antioxidant properties Mechanistically it reduces intracellular reactive oxygen species (ROS) levels and mitigates apoptosis in response to oxidative agents such as hydrogen peroxide Through its modulation of oxidative stress pathways N-trans-Feruloyltyramine is of interest in studies exploring the pathogenesis and intervention of neurodegenerative disorders and cancer associated with oxidative damage This compound thus serves as a useful tool for investigating oxidative stress and its cellular effects in biomedical research
Medchemexpress LLC GB111-NH2 hydrochloride | 99.3% | 610.14 | 100 MG
GB111-NH2 hydrochloride is a cysteine cathepsin inhibitor and can be used for cancer study.
- Functions as a cysteine cathepsin inhibitor
- Suitable for cancer research
- Chemical formula C33H40ClN3O6
- Appears as a solid, white to off-white powder
- Soluble in DMSO at 125 mg/mL (in vitro)
- Soluble in 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline at 5 mg/mL (in vivo)
- Classified under metabolic enzyme/protease and cathepsin
Medchemexpress LLC OTS186935 hydrochloride | 99.6% | 522.31 | 10 MG
OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. It demonstrates significant inhibition of tumor growth in mouse xenograft models without detectable toxicity. This product also regulates the production of γ-H2AX in cancer cells. This product is for research use only and is not sold to patients.
- IC50 & Target: 6.49 nM (SUV39H2)
- Inhibits A549 cell growth with an IC50 of 0.67 μM
- Shows growth suppressive effects in human cancer cell line derived xenograft models
- Yielded a tumor growth inhibition of 60.8% without significant body weight loss or toxicity in female BALB/cAJcl-nu/nu mice
Medchemexpress LLC JBI-589 | 2308504-22-3 | C29H28FN5O | 5 MG
JBI-589 is a non-covalent, orally bioavailable, isoform-selective inhibitor of PAD4 (Protein Arginine Deiminase 4). It has been shown to reduce CXCR2 expression and block neutrophil chemotaxis. This compound can decrease primary tumors and metastases, and also enhance the anti-tumor effect of checkpoint inhibitors. JBI-589 is suitable for use in cancer research.
- Reduces CXCR2 expression and blocks neutrophil chemotaxis
- Decreases primary tumors and metastases
- Enhances anti-tumor effect of checkpoint inhibitors
- Suitable for cancer research
- Inhibits citrullination of histone H3 in Phorbol 12-myristate 13-acetate-induced mouse neutrophils
- Significantly inhibits growth of primary tumors in mouse models
Medchemexpress LLC Triethylene glycol monobenzyl ether | 55489-58-2 | MFCD02093556 | 99.8% | 240.30 g/mol | C13H20O4 | 10 G
Triethylene glycol monobenzyl ether is a polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of proteolysis-targeting chimeras (PROTACs). It is a colorless to light yellow liquid with a molecular weight of 240.30 g/mol and CAS number 55489-58-2.
- PEG-based linker suitable for PROTAC synthesis
- High purity suitable for research applications
- Liquid form enables facile coupling and handling
- Commonly supplied in small laboratory package sizes for synthetic use
Chem-Impex International, Inc. 6-Methoxyindole | 3189-13-7 | MFCD00022780 | 1G
6-Methoxyindole, 3189-13-7, MFCD00022780, 1G
Medchemexpress LLC Pkr-in-c51 (compound 51) | 1314594-23-4 | 99.8% | 367.45 g/mol | C23H21N5 | 25 MG
PKR-IN-C51 (compound 51) is an ATP-competitive inhibitor of double-stranded RNA-activated protein kinase (PKR) that suppresses intracellular PKR activation in primary mouse macrophages. It has an IC50 of 9 μM and is supplied as a solid or as a DMSO solution for research use only.
- ATP-competitive PKR inhibitor; IC50 9 μM.
- Molecular weight 367.45 g/mol; formula C23H21N5.
- High purity (≈99.8%).
- Available as solid (25 MG) and as 10 mM solution in DMSO.
- Storage: solid at 4°C protected from light; in solvent store at -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or clinical use.
Medchemexpress LLC Octaethylene glycol monomethyl ether | 25990-96-9 | MFCD06797152 | 99.8% | 384.46 g/mol | C17H36O9 | 1 G
Octaethylene glycol monomethyl ether is a methyl-terminated polyethylene glycol (PEG8) linker used in the synthesis of PROTACs and other bioconjugates. It is a colorless liquid with CAS 25990-96-9, molecular formula C17H36O9, and molecular weight 384.46 g/mol. Typical purity is 99.84% and it is commonly supplied in 1 g packaging.
- Flexible, hydrophilic spacer for linker construction.
- Methyl-terminated ether group for stable end-capping.
- High purity suitable for synthetic applications.
- Provides analytical documentation such as COA, HNMR, and MS.
- Usable as a PEG-based building block in medicinal chemistry and bioconjugation.
Apexbio Technology LLC 4-Thio-dTTP 100ul (100 mM)
4-Thio-dTTP is a nucleotide analog structurally similar to thymidine triphosphate (dTTP) It incorporates into DNA strands during enzymatic synthesis modifying nucleic acid interactions and affecting the activities of enzymes involved in DNA replication and repair 4-Thio-dTTP exerts its biological activity through incorporation into DNA enabling the study of DNA polymerase fidelity replication kinetics enzyme-substrate interactions and mechanisms of DNA damage responses Based on these biochemical properties 4-Thio-dTTP holds research potential in applications such as investigating DNA synthesis regulation enzymatic mechanisms and pathways related to cancer and genomic instability
Medchemexpress LLC Octaethylene glycol | 5117-19-1 | MFCD00698694 | 100.0% | 370.44 g/mol | C16H34O9 | 5 G
Octaethylene glycol is a polyethylene glycol (PEG) linker composed of eight ethylene glycol units. It is a hydrophilic spacer used in chemical synthesis, commonly as a linker for proteolysis targeting chimeras (PROTACs) and other bioconjugation applications. The substance is a diol with terminal hydroxyl groups and is soluble in water and polar organic solvents.
- Cas number 5117-19-1.
- Molecular formula C16H34O9.
- Molecular weight 370.44 g/mol.
- High purity suitable for research use.
- Functional groups: terminal hydroxyls for conjugation.
- Uses: peg-based linker for PROTAC synthesis and bioconjugation.
- Available in small lab-scale quantities (5 G pack).
Medchemexpress LLC 2-Deoxy-2 2-difluoro | 10g
2-Deoxy-2 2-difluoro-D-erythro-pentonic acid -Lactone 3 5-dibenzoate is a chemically synthesized fluorinated carbohydrate derivative that can be used in glycobiology research[1]
Medchemexpress LLC 2-deoxy-2,2-difluoro-D-erythro-pentonic acid γ-lactone 3,5-dibenzoate | 122111-01-7 | MFCD08458308 | ≥97.0% | 376.31 | C19H14F2O6 | 5 G
2-Deoxy-2,2-difluoro-D-erythro-pentonic acid γ-lactone 3,5-dibenzoate is a chemically synthesized fluorinated carbohydrate derivative used in glycobiology and carbohydrate chemistry research. It is supplied as a white to off-white solid with high reported purity suitable for laboratory applications.
- Chemical class: Fluorinated carbohydrate γ-lactone.
- Cas number: 122111-01-7.
- Chemical formula: C19H14F2O6.
- Molecular weight: 376.31 g/mol.
- Purity: ≥97.0%.
- Appearance: White to off-white solid.
- Storage: Store at room temperature (solid); in solvent, store at -80°C (2 years) or -20°C (1 year).
- Available pack sizes: 5 g, 10 g, 25 g, 50 g, 100 g.